1·The Molecular Genetics of schizophrenia (MGS) consortium pinpointed an association between schizophrenia and genes in the chromosome-6 region that mediate gene expression, such as histones.
精神分裂症的分子遗传学院会(MGS)精确确定了精神分裂症和6号染色体区域上的基因间的联系,它介导基因表达,比如组蛋白。
2·Where long strands of DNA are tightly coiled around a group of proteins called "histones."
其中的DNA长链盘绕紧密围绕一个名为“组蛋白的蛋白质组。”
3·Histones are proteins involved in regulating genes being turned on and off.
组蛋白是涉及到调控基因的蛋白质。
4·Histones organize the DNA and keep it from getting tangled, much like thread wrapped around a spool.
组蛋白组织DNA并防止它杂乱,很像线缠在线轴上。
5·Past structural studies of methylation were hindered by the extreme difficulty of constructing homogeneous samples of histones bearing methyl groups attached to specific lysine residues.
过去甲基化的结构研究被阻碍的原因是因为很难制备组蛋白特定部位赖氨酸甲基化的均一样品。