1·Objective To investigate the effects of target gene mutations on the quinolones resistance in Escherichia coli.
目的探讨大肠埃希菌靶位基因突变对喹诺酮类药物耐药的影响。
2·Quinolones gets more and more use in the clinic for its advantages of high activity, broad spectrum and the convenience in the taking, et al.
喹诺酮类药物(如氧氟沙星、诺氟沙星、环丙沙星等)抗生素以其高效、广谱、服用方便等优点在临床上发挥了越来越重要的作用。
3·AIM: To evaluate the relation between the relative toxicity, chondrotoxicity of some kinds of quinolones on chondrocytes of younger rabbits and the concentration, animal age, treatment duration.
目的：评价几种喹诺酮类药物对幼龄兔软骨细胞的相对毒性，软骨毒性与浓度、时间、年龄的关系。
4·This drug is not for patients who have shown hypersensitivity to quinolones.
对喹诺酮类药物过敏的患者忌用。
5·Conclusion The elderly and special populations should be carefully chosen to use quinolones;
结论老年人及特殊人群应慎重选择使用喹诺酮类药物；