方法:将蒿甲醚的不同浓度作用于体外培养基中的阴道毛滴虫,并与甲硝唑作比较。
他们用青蒿素的一种衍生物——蒿甲醚代替青蒿素,协助改进了固定复方药。
较高浓度的蒿甲醚和青蒿琥酯有较缓慢抑制虫体活动的作用,并可杀死部分成虫;
目的评价蒿甲醚对小鼠体内埃及血吸虫皮层的损害作用。
七项试验比较了蒿甲醚和奎宁(1220名儿童),两项试验比较了蒿乙醚和奎宁(194名儿童)。
1·But the three types of antimalarial available in suppository form - artemisinin, artesunate and artemether - have never been compared for effectiveness.
但是三种抗疟药——青蒿素、青蒿琥酯和蒿甲醚——栓剂的有效性从未进行过比较。
2·Objective To evaluate the efficacy and side effects of artemether combined with primaquine in the treatment of falciparum malaria.
目的观察蒿甲醚伍用伯氨喹治疗恶性疟的疗效和副作用。
3·No apparent changes in hepatic and renal functions, reticulocyte count or electrocardiograph was evidenced after completion of artemether administrartion.
口服蒿甲醚对肝、肾功能、网织红细胞和心电图未见明显异常。
4·Artemisinins are the major drugs of antimalarial. Its derivatives include artesunate, artemether, dihydroartemisinin and etc. Artemisinins exert their antimalarial activity by iron-mediated cleavage.
青蒿素类药物是治疗疟疾的主要药物,其衍生物有青蒿琥酯、蒿甲醚和二氢青蒿素等,主要的作用机制是通过铁离子介导的细胞损伤。