巨噬细胞吞噬红细胞后破坏细胞膜,血红蛋白被转化为血红素和球蛋白。
血红蛋白的合成和释放、红细胞的产生和生存、或代谢机制受到干扰则会导致疾病。
多余的血红蛋白和铁元素会在尿液中排出(血红蛋白尿)。
大约1%的衰老红细胞在血液循环中发生溶血,释放游离血红蛋白。
1·This is quickly converted to Hgb dimers that bind to haptoglobin and are transported to the liver, where they are metabolized in the same manner as products from RBC removed by phagocytosis.
然后迅速转化为血红蛋白二聚体与肝球蛋白质结合,并运送到肝脏经吞噬作用除去。
2·Results For most cardionephric disharmony type:the sum of RBC, WBC, HGB, PLT decreased, Urine protein increased, left chamber enlargement, tachycardia;
结果心肾不交型多见红细胞、白细胞、血红蛋白、血小板降低,尿蛋白增高,左房增大,心动过速;