结果:我院抗菌药物使用主要以青霉素类、头孢菌素类、大环内酯类、氟喹诺酮类为主。
结果:抗菌药物使用以青霉素类、头孢菌素类为主,占总用药量的95%左右。
在三岁以前,胃酸分泌处于低水平,对酸不稳定的药物,例如青霉素的吸收会增强。
对青霉素类及其含酶抑制药物的耐药率略有波动,大致呈下降趋势。
1·Pharmacokinetic data suggest that normal doses of penicillins, cotrimoxazole and gentamicin are safe in malnourished children, while the dose or frequency of chloramphenicol requires adjustment.
药物动力学数据表明,正常剂量的青霉素、复方磺胺甲恶唑和庆大霉素对于营养不良的儿童是安全的,而氯霉素的剂量或服用频率需要调整。
2·It is important to elucidate the mechanisms of allergic reaction to penicillins and improve the diagnostic methods.
因此,探讨青霉素过敏反应的发生机制,提高临床诊断率,具有十分重要的意义。
3·The resistance of Abi to penicillins and to their inhibitedcompounds fluctuated slightly and downtrended more or less.
对青霉素类及其含酶抑制药物的耐药率略有波动,大致呈下降趋势。
4·The combined therapy with penicillins or vancomycin plus an aminoglycoside can not be used in 50.0% enterococci infection.
有5 0 .0 %的肠球菌感染不能用青霉素或粘肽类与氨基糖苷类联合用药。
5·Objective: To understand the safety of oral penicillins agents.
目的:了解青霉素类口服制剂的安全性问题。