1·This is the bottom line: We can embrace this accord, take a substantial step forward, continue to refine it and build upon its foundation.
我们的底线是：我们接受这个协议，向前迈出实质性的一步，继续使之完善，在这个基础上再接再励。
2·The proceeds reclaim of venture capital is the substantial step of whole operational process of venture capital, which is crucial to the success of venture capital.
创业投资收益回收是整个创业投资运作的核心阶段，关系到创业投融资过程的成败。
3·As I said earlier this week in New York, all nations have a responsibility to meet this challenge, and together, we have taken a substantial step forward in meeting that responsibility.
正如本周早些时候我在纽约所言，所有国家都有责任迎接这一挑战，通过共同努力，我们在履行此项责任方面向前迈出了一大步。
4·At every step from the goals to the evaluation and at every working operational point should there be a substantial exchange of feedback.
每一个步骤，从目标到评价，每一个工作操作点都应该有一个实质性的反馈交流。
5·The data show that a two-step process causes the substantial rise of killer electrons.
数据显示了导致致命电子明显增长的两步过程。
6·There is a step up trend of seriousness of diseases in different levels of hospitals, but the difference is not substantial.
各等级医院收治病人的严重程度呈现一定梯度，但差异并不明显。