1·The sickled cells are prone to stick together plugging smaller vessels and leading to decreased blood flow with ischemia.
镰状细胞易于粘连在一起，堵塞小血管，血流减少而导致局部缺血。
2·The sickled cells are prone to stick together, plugging smaller vessels and leading to decreased blood flow with ischemia.
镰状细胞易于粘连在一起，堵塞小血管，血流减少而导致局部缺血。
3·With the removal of oxygen from sickle hemoglobin, the red blood cell deforms into a sickled shape. This sickling damages the RBC membrane and increases the likelihood of rupture and anemia.
随着镰珠蛋白中氧的去除，红细胞变形成镰状，红细胞膜受到破坏，破裂的可能性增加，从而导致贫血。