1·Of the 44 patients, 50% also received adjunctive therapy with memantine.
在这44名患者中,其中50%还接受美金刚辅助治疗。
2·To test this idea, she asked a number of patients undergoing amputation to take a drug called memantine.
为了检验这个想法,她让进行截肢的病人服用一种叫美金刚胺(Memantine)的药物。
3·Thirteen patients took memantine for four weeks after their amputations (and sometimes just before, as well).
13名病人在他们截肢之后(有些病人也在截肢前)服用美金刚胺持续4个星期。
4·To their delight, they discovered that memantine not only reduced changes in the brain, it also decreased both the incidence and the intensity of phantom pain.
让他们欣慰的是,他们发现美金刚胺不但减少了大脑的改变,而且也降低了患肢疼痛的次数和强度。
5·Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%.
以1,3-二甲基金刚烷为原料,经溴化、 乙腈和硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚,总收率6 7。8%。