competitive inhibition

从而阻止底物与酶结合
常用释义
竞争性抑制:一种酶抑制剂的作用方式,它通过与酶的活性部位竞争结合,从而阻止底物与酶结合,降低酶的催化活性。

例句

1·The paratope mapping of antibodies was determined by competitive inhibition in radioimmunoassay.

通过放射免疫测定中的竞争性抑制来确定抗体的互补位图。

2·Meanwhile, many drugs can influence the activity of CYP2D6 by competitive inhibition or induction, which is easy to cause interaction in coadministration.

而且CYP2D6能被多种药物竞争性抑制和诱导,药物联用时易产生相互作用。

3·Methods: the colloidal gold strip for specific sulfadimidine was developed successfully on the basis of competitive inhibition immunochromatography mechanism.

方法:应用竞争抑制免疫层析原理,研制磺胺二甲基嘧啶胶体金试纸条。

4·In the competitive inhibition experiment, it showed that rapamycin and FK506 could bind this protein competitively and rapamycin had better binding capacity than FK506.

竞争性抑制实验显示雷帕霉素与FK506和该蛋白质的结合存在竞争性,且雷帕霉素与该蛋白质的结合能力比FK506强。

5·QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction.

槲皮素竞争性抑制CYP3A 2右美沙芬N脱甲基反应,非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

6·METHODS The paratope mapping of antibodies was determined by competitive inhibition in radioimmunoassay and the sequences of variable regions among the antibodies were compared.

应用放射免疫竞争抑制试验测定抗体的配位特异性,并对抗体的可变区序列进行比较。

7·Competitive INHIBITION Competitive inhibitors compete with substrate for an enzyme's active site, lowering the enzyme's likelihood of binding substrate and slowing the observed reaction velocity.

竞争性抑制竞争性抑制剂与底物竞争酶的活性部位,降低酶的约束力基板的可能性,并观察到的反应速度放缓。

8·Kinetic studies of AG114 inhibition on recombinant human CK2 showed that the inhibition was mixed competitive with GTP and noncompetitive with casein.

AG114对重组人ck2的动力学研究表明:它与GTP呈混合竞争性抑制作用,与酪蛋白呈非竞争性抑制作用。

9·Kinetic studies of AG1112 on recombinant human CK2 showed that the inhibition was mixed (competitive is dominant) with GTP and noncompetitive with casein.

AG 1112对重组人ck2的动力学研究表明:它与GTP和酪蛋白分别呈混合性和非竞争性抑制作用。

10·A kinetics model was developed for predicting and simulating immobilized cellulase performance, which follows Michaelis_Menten kinetics with competitive product inhibition.

建立了固定化纤维素酶的反应动力学模型,该模型以米氏方程为基础并考虑了产物竞争性抑制的影响。