1·1346年的飓风引起海啸并摧毁了城镇。
In 1346 a hurricane whipped up the sea to destroy the town.
2·结果在1例患者中发现第11外显子的1346 （G>C）的错义突变，为一种纯合突变；
Results A missense mutation of 1346(G>C) in exon 11, which was a homozygotic mutation, was identified in one patient;
3·尽管经历沧桑，这座中世纪的古堡（包括古堡下的地牢）还是在战火纷飞的年代中幸存了下来，据说在1346年，苏格兰国王大卫二世用这个地牢关押过犯人。
The mansion's medieval caves, however, survived the conflict, including the dungeon, where King David II of Scotland was reportedly held prisoner in 1346.