1·They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.
他们将原癌基因诱导的淋巴瘤移植到野生型小鼠,然后在淋巴瘤细胞启动p53表达。
2·That is because one of Dr Yamanaka's transcription factors, c-Myc, sometimes has the unfortunate side-effect of causing cancer.
Yamanaka博士发现的转录因子有时会导致癌症的产生。
3·The first involved safety, since the technique relied on potentially harmful genetic manipulation, and worse yet, the insertion of two known cancer-causing genes (c-Myc and Oct4).
其一是安全性的问题,因为该技术是基于具有潜在伤害性的基因操作,并且引入了2个致癌基因(c - My c and Oct4)。