其次，未消化的食物颗粒会渗漏过肠壁进入你的身体循环。
在APTE早期，这些细胞因子对全身血循环的影响较小。
这样，药物在进入体循环可供测量之前就可能被代谢（首过代谢）。
1·The volume of the systemic circulation is about 7 times that of the pulmonary system.
体循环的容量约为肺循环容量的7倍。
2·They are usually asymptomatic when confined to the heart but may produce complications due to embolism to the cerebral or systemic circulation.
血栓局限于心脏时一般并无症状，但栓子脱落到脑血管或体循环将会引起并发症。
3·As it degrades over the course of months, the tube "gives the space for cells to grow and regenerate to extend systemic circulation, " said Alejandro Nieponice, who also worked on the study.
在这个研究中工作的Alejandro Nieponic说，随着数月的病程试管可降解，它可给细胞生长的空间，再生可以伸展到体循环。