1·Autophagy reduces inflammation but at the same time permits the clearance of microbial infection.
自噬可减轻炎症反应,同时也允许清除导致感染的微生物。
2·This article summarizes the role of autophagy in Tumorigenesis, Metastasis and Therapy.
本文对自噬在肿瘤发生、转移与治疗中的作用进行综述。
3·Paradoxically, although autophagy is primarily a protective process for the cell, it can also play a role in cell death.
矛盾的是,尽管自噬主要对于细胞起一种保护过程中,它也在细胞死亡中起着一定的作用。
4·This Review summarizes recent advances in understanding the physiological functions of autophagy and its possible roles in the causation and prevention of human diseases.
本文总结最新进展,以便了解自噬的生理功能,以及它在因果关系中与人类疾病的预防中所可能发挥的作用。
5·Recent evidence suggests that autophagy provides a protective function to limit tumour necrosis and inflammation and to mitigate genome damage in tumour cells in response to metabolic stress.
近来的证据显示:自噬提供了一个保护性功能来限制肿瘤坏死和炎症,同时减轻了肿瘤细胞内的染色体损伤来回应代谢性应激。
1·According to Li, autophagy is the only known process that gets rid of abnormal proteins within cells. "Enhancing this pathway may be key to treating Parkinson's," she says.
李敏表示,自吞噬是清除细胞内异常蛋白质的唯一途径。“增强这一途径可能是治疗帕金森症的关键。”她如是说。
2·Thus, the study on autophagy is of great significance.
因此,对自吞噬的研究有重要意义。
1·PEA-15 expression inhibited proliferation, and cell cycle analysis did not reveal apoptosis but did reveal autophagy, which was confirmed by an increase in LC3 cleavage.
研究表明PEA - 15表达抑制了细胞增殖,细胞循环分析没有揭示凋亡而揭示了自体吞噬,这是通过LC3的切割确认的。
2·Autophagy appears to involve an active participation of the vacuolar membranes.
自体吞噬似乎与液泡膜的积极参加有关。